ParvoDB ID PV028547 GenBank Accession KC823115
Subfamily Parvovirinae Genus Bocaparvovirus
Species Bocaparvovirus primate1 Sequence Length 5146
Definition Human bocavirus strain Irish, complete genome. Submission Date 2013-03-26
Strain Name Irish Sampling Date 2012
Sampling Country Ireland Location Ireland
Submitted By Sadeghi,M., Kantola,K., McCaughey,C., Finnegan,D., Hedman,L., Soderlund-Venermo,M. and Hedman,K. Submitting Institution Department of Virology, Haartman Institute, University of Helsinki, Haartmaninkatu 3, Helsinki, Helsinki FIN-00014, Finland
Original Host Homo sapiens Sample Type Blood, tracheal aspirate, and sputum samples
Standardized Host Name Homo sapiens Host Tax Rank species
Standardized Host Class Mammalia Standardized Host Order Primates
Environmental Origin - N/A - Reagent Origin - N/A -
Number Reagent/Consumables Purpose PMID/Url Reference
1 Azacitidine Used for treatment of relapsed chronic lymphocytic leukemia and secondary hypogammaglobulinemia. 23903541 View Related Publication
2 Co-trimoxazole Administered as a prophylactic dose for unspecified infection prevention.
3 Intravenous immunoglobulin Administered monthly as a prophylactic treatment for recurrent infections due to hypogammaglobulinemia.
4 Oral corticosteroid Started in view of the patient’s history of chronic obstructive pulmonary disease.
5 Clarithromycin Administered intravenously, presumably for treating bacterial pneumonia or an atypical chest infection.
6 Piperacillin with tazobactam Administered intravenously in conjunction with clarithromycin to treat suspected bacterial pneumonia.
7 Fluconazole Given to treat presumed pharyngeal thrush.
8 Meropenem Administered when the patient’s condition worsened to cover for multidrug-resistant bacterial infections.
9 Teicoplanin Introduced along with Meropenem to broaden antimicrobial coverage.
10 High-dose co-trimoxazole Introduced to cover possible Pneumocystis jirovecii pneumonia.
11 Respiratory samples (sputum and tracheal secretions) Collected post-mortem for pathogen detection by PCR/quantitative PCR.
12 Blood sample Collected post-mortem on the day patient died to assess pathogen DNA levels.
13 High-fidelity PCR Used to clone the viral genome from the sputum sample for almost entire HBoV1 genome sequence determination.
14 Virus-like particles Used in competition enzyme immunoassay (EIA) to test for IgG and IgM antibodies against HBoV1 to HBoV4.